Modeling cumulative incidence function for competing risks data

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چکیده

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Cumulative incidence in competing risks data and competing risks regression analysis.

Competing risks occur commonly in medical research. For example, both treatment-related mortality and disease recurrence are important outcomes of interest and well-known competing risks in cancer research. In the analysis of competing risks data, methods of standard survival analysis such as the Kaplan-Meier method for estimation of cumulative incidence, the log-rank test for comparison of cum...

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Cumulative incidence estimates in the presence of competing risks.

When competing risks are present, the appropriate estimate of the failure probabilities is the cumulative incidence. stcompet creates new variables containing the estimate of this function, its standard error, and ln(− ln) transformed confidence bounds. Two examples are presented to illustrate the use of the new command and some key features of the cumulative incidence.

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Comparison of competing risks models based on cumulative incidence function in analyzing time to cardiovascular diseases

BACKGROUND Competing risks arise when the subject is exposed to more than one cause of failure. Data consists of the time that the subject failed and an indicator of which risk caused the subject to fail. METHODS With three approaches consisting of Fine and Gray, binomial, and pseudo-value, all of which are directly based on cumulative incidence function, cardiovascular disease data of the Is...

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Non-parametric inference for cumulative incidence functions in competing risks studies.

In the competing risks problem, a useful quantity is the cumulative incidence function, which is the probability of occurrence by time t for a particular type of failure in the presence of other risks. The estimator of this function as given by Kalbfleisch and Prentice is consistent, and, properly normalized, converges weakly to a zero-mean Gaussian process with a covariance function for which ...

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The cumulative incidence is the probability of failure from the cause of interest over a certain time period in the presence of other risks. A semiparametric regression model proposed by Fine and Gray (1999) has become the method of choice for formulating the effects of covariates on the cumulative incidence. Its estimation, however, requires modeling of the censoring distribution and is not st...

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ژورنال

عنوان ژورنال: Expert Review of Clinical Pharmacology

سال: 2008

ISSN: 1751-2433,1751-2441

DOI: 10.1586/17512433.1.3.391